Search results for "SARS Virus"

showing 3 items of 3 documents

An Italian Guidance Model for the Management of Suspected or Confirmed COVID-19 Patients in the Primary Care Setting

2020

An outbreak of Severe Acute Respiratory Syndrome Coronavirus 2 started in China's Hubei province at the end of 2019 has rapidly become a pandemic. In Italy, a great number of patients was managed in primary care setting and the role of general practitioners and physicians working in the first-aid emergency medical service has become of utmost importance to coordinate the network between the territory and hospitals during the pandemic. Aim of this manuscript is to provide a guidance model for the management of suspected, probable, or confirmed cases of SARS-CoV-2 infection in the primary care setting, from diagnosis to treatment, applying also the recommendations of the Italian Society of Ge…

2019-20 coronavirus outbreakCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)PopulationSARS virusReviewsevere acute respiratory syndromePrimary care030204 cardiovascular system & hematologyDisease Outbreakscoronavirus infection03 medical and health sciencescoronavirus infections0302 clinical medicinegeneral practitionersMultidisciplinary approachSARS viruPandemicHumansMedicine030212 general & internal medicineeducationPandemicseducation.field_of_studyDisease Outbreakbusiness.industrylcsh:Public aspects of medicinePublic Health Environmental and Occupational HealthCOVID-19Outbreaklcsh:RA1-1270medicine.diseaseprimary health careItalygeneral practitionerPractice Guidelines as TopicPublic HealthPreventive MedicineMedical emergencybusinessHumansevere acute respiratory syndrome coronavirus 2Frontiers in Public Health
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Delaying surgery for patients with a previous SARS-CoV-2 infection

2020

With at least 28 elective million operations delayed during the first three months of the COVID-19 pandemic, the number of patients who will require surgery after a previous SARS-CoV-2 infection is likely to increase rapidly1. Operating on patients with an active perioperative SARS-CoV-2 infection is now known to carry a very high pulmonary complication and mortality rate2. Urgent information is needed to guide whether postponing surgery in patients with a previous SARS-CoV-2 infection leads to a clinical benefit, and the optimal length of delay.

SARS Virus Coronavirus Severe Acute Respiratory Syndrome cancersurgery pandemic infectionSettore MED/06 - Oncologia MedicaSettore MED/18 - CHIRURGIA GENERALESettore MED/29 - CHIRURGIA MAXILLOFACCIALECOVID-19. Global surgery.Settore MED/19 - Chirurgia PlasticaComorbidity030230 surgeryCovidCOVID-19 / epidemiologysurgery0302 clinical medicineNeoplasms / surgeryNeoplasmsCOVID-19; Comorbidity; Humans; Neoplasms; Surgical Procedures Operative; Pandemics; SARS-CoV-2; Time-to-TreatmentProspective cohort study610 Medicine & healthCOVID-19/epidemiologymedicine.diagnostic_testSurgery sars-cov-2 covid surg surgery pandemic infectionPulmonary ComplicationSARS cov 2Covid19Surgical Procedures Operative / methodsOperativesurgery; Sars-CoV-2Surgical Procedures OperativeSurgery sars-cov-2Neoplasms / epidemiologyCohort studyHumanmedicine.medical_specialtySciences du Vivant [q-bio]/Médecine humaine et pathologieNOTime-to-TreatmentThroat culture03 medical and health sciencesSettore MED/28 - Malattie OdontostomatologichemedicineResearch LetterHumansElective surgeryGeneralPandemicscovid surgSurgical ProceduresPandemicbusiness.industrySARS-CoV-2No key words availablePostoperative complicationCOVID-19Perioperativemedicine.diseaseSurgeryPneumoniaSettore MED/40 - GINECOLOGIA E OSTETRICIANeoplasmSurgical Procedures Operative/methodsSurgerybusinessNeoplasms/epidemiology[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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Is the Rigidity of SARS-CoV-2 Spike Receptor-Binding Motif the Hallmark for Its Enhanced Infectivity? Insights from All-Atom Simulations

2020

The severe acute respiratory syndrome coronavirus (SARS-CoV-2) pandemic is setting the global health crisis of our time, causing a devastating societal and economic burden. An idiosyncratic trait of coronaviruses is the presence of spike glycoproteins on the viral envelope, which mediate the virus binding to specific host receptor, enabling its entry into the human cells. In spite of the high sequence identity of SARS-CoV-2 with its closely related SARS-CoV emerged in 2002, the atomic-level determinants underlining the molecular recognition of SARS-CoV-2 to the angiotensin-converting enzyme 2 (ACE2) receptor and, thus, the rapid virus spread into human body, remain unresolved. Here, multi-m…

LettervirusesAmino Acid MotifsPneumonia ViralVirus Attachment02 engineering and technologyPlasma protein bindingBiologyPeptidyl-Dipeptidase AMolecular Dynamics SimulationVirus03 medical and health sciencesBetacoronavirusViral ProteinsProtein structureViral envelopeGlobal healthHumansGeneral Materials SciencePhysical and Theoretical ChemistryReceptorProtein Structure QuaternaryPandemics030304 developmental biologyGlycoproteinschemistry.chemical_classificationGeneticsInfectivity0303 health sciencesSARS-CoV-2virus diseasesCOVID-19Hydrogen Bonding021001 nanoscience & nanotechnologySARS VirusProtein Structure TertiarySevere acute respiratory syndrome-related coronaviruschemistrySettore CHIM/03 - Chimica Generale E InorganicaQuantum TheoryAngiotensin-Converting Enzyme 20210 nano-technologyGlycoproteinCoronavirus InfectionsProtein Binding
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